Role of ammonia in predicting the outcome of patients with acute-on-chronic liver failure

Table 3 Multivariate analysis of the predictive factors for in-hospital mortality

	Variables in the equation
Step 11	B	SE	Wald	df	Sig	Exp (B)	95%CI for EXP (B)
							Lower	Upper
AKI	0.593	0.577	1.055	1	0.304	1.809	0.584	5.607
MELD score ≥ 22.5	0.815	0.610	1.787	1	0.181	2.259	0.684	7.463
Child-Pugh score ≥ 12.5	0.366	0.568	0.415	1	0.520	1.442	0.473	4.394
AARC score ≥ 8.5	1.849	0.642	8.305	1	0.004	6.354	1.807	22.349
HE grade III or IV	1.154	0.628	3.383	1	0.066	3.172	0.927	10.853
Venous ammonia ≥ 152 μmol/L	-1.813	0.508	12.763	1	0.000	0.163	0.060	0.441
Constant	-2.795	1.368	4.172	1	0.041	0.061

¹Variable(s) entered on step 1: AKI, MELD score ≥ 22.5, Child-Pugh score ≥ 12.5, AARC score ≥ 8.5, HE grade III or IV, Venous ammonia ≥ 152 μmol/L.AKI: Acute kidney injury; MELD: Model for end-stage liver disease; AARC score: APASL ACLF Research Consortium score; HE: Hepatic encephalopathy; Sig: Significant; SE: Standard error; CI: Confidence interval.