Synchronous concomitant pancreatic acinar cell carcin and gastric adenocarcinoma: A case report and review of literature

Table 1 Reported cases of synchronous gastric and pancreatic tumors

Ref.	Age	Gender	Gastric tumorlocation	Gastric histology	Pancreatic tumor location	Pancreatic histology	Treatment
Eriguchi et al[7], 2000	76	Male	Upper gastric angle	Moderately differentiated tubular adenocarcinoma	Not mentioned	Well to moderately differentiated tubular adenocarcinoma	Surgically treated
Kubota et al[8], 2009	67	Male	Not mentioned	Moderately differentiated adenocarcinoma	Not mentioned	Absence of pancreatic histology	Chemotherapy: S-1, paclitaxel and lentinan
Meng et al[9], 2011	42	Male	Gastric antrum	Gastric GIST	Pancreatic head	Pancreatic GIST	Surgically treated
Shen et al[10], 2010	72	Female	Major gastric curvature	Gastric GIST	The head of the pancreas	Poorly differentiated PDAC; malignant fibrous histiocytoma	Surgically treated
Muroni et al[11], 2010	73	None	Gastric antrum and pyloric portion	Moderately differentiated adenocarcinoma	Uncinate portion of the pancreas	Poorly differentiated PDAC	Surgically treated
Dasanu et al[12], 2011	75	Male	Not mentioned	GIST	The head of the pancreas	Moderately to poorly differentiated carcinoma	Surgically treated
Kourie et al[13], 2013. case 1	56	Male	Anterior part of the antrum	Poorly differentiated adenocarcinoma with independent mucus-secreting cells	The head of the pancreas	Necrotic ductal adenocarcinoma	Chemotherapy: Folfirinox
Kourie et al[13], 2013. case 2	62	Male	Gastric wall of the greater curvature	Gastric adenocarcinoma with mucinous component	Tail of the pancreas	Tubular adenocarcinoma (ck7+; ck20-; ck19+)	Chemotherapy: Folfirinox
Ohtsubo et al[14], 2013	77	Male	In the middle of stomach	Adenocarcinoma stage IB, T2bN0M0	Pancreatic head	Adenocarcinoma stage IIA, T3N0M0	Treated with chemotherapy: S-1
Baba et al[15], 2015	70	Male	The fundal region and greater curvature of the stomach	Low grade gastric calcified stromal tumor (GIST)	The head of the pancreas	Adenocarcinoma	Surgically treated
Ghothim et al[16], 2015. case 1	73	Male	The antrum of the stomach	Adenocarcinoma (pT1N1M0 stage IB, G2)	The head of the pancreas	Ductal pancreatic cancer. (pT2N1M0, stage IIB, G3)	Surgically treated; gemcitabine in six cycles
Ghothim et al[16], 2015. case 3	74	Male	The antrum of the stomach	Gastric adenocarcinoma diffuse type (pT2bN2M0, G3)	Pancreatic head	Papillary mucinous carcinoma (pT2N0M0, stage IB, G1)	Surgically treated; Radiotherapy and chemotherapy
Fiore et al[17], 2015. case 1	63	Male	Not mentioned	Gastric GIST (T2N0)	Pancreatic head	Adenocarcinoma (T2N0)	Surgically treated
Santos-Fernández et al[18], 2015	64	Female	Prepiloric antral ulcer	Well differentiated gastric adenocarcinoma	Pancreatic tail	Pancreatic adenocarcinoma	Not mentioned
Arabadzhieva et al[19], 2016	60	Female	In the pyloric area	Gastric GIST	Pancreatic body	Pancreatic neuroendocrine tumor	Surgically treated
Yonenaga et al[20], 2016	63	Male	Antrum of the stomach	Poorly differentiated adenocarcinoma.	The body of the pancreas	PACC	Chemotherapy
Our case, 2021	69	Male	Antrum of the stomach	Gastric adenocarcinoma	The tail of the pancreas	PACC	Surgically treated; Chemotherapy

GIST: Gastrointestinal stromal tumors; PDAC: Pancreatic ductal adenocarcinoma; PACC: Pancreatic acinar cell carcinoma.