Metachronous mixed cellularity classical Hodgkin’s lymphoma and T-cell leukemia/lymphoma: A case report

Table 2 Previously reported and current cases of classical metachronous Hodgkin lymphoma and peripheral T-cell lymphoma

Age, y/sex	One (EBV)	Therapy for one	Other (EBV)	Therapy for other	Interal (mo)	BM infiltration	Outcome	Ref.
32/M	CHL (+)	ABVD	PTCL (-)	Unknown	24	Unknown	Unknown	Brown et al[11], 2004
77/F	PTCL (nd)	CHOP	CHL (nd)	Radiation therapy	48	Unknown	Unknown	Brown et al[11], 2004
34/F	CHL (?)	ABVD	PTCL (+)	CHOP, IVE, intermediate-dose MTX, ASCT, BV	47	No	Died after 26 mo	Meconi et al[12], 2020
54/M	CHL (nd)	MOPP, ABVD	PTCL (nd)	Unknown	24	No	Unknown	Wlodarsk et al[13], 1993
76/F	CHL (+)	ABVD	PTCL (+)	CHOP	108	No	Died after 5 mo	Oka et al[14], 2011
37/M	PTCL (nd)	IVAM, BEAM, ASCT	CHL (+)	ABVD	60	Yes	Died after 17 mo	Park et al[15], 2013
64/F	CHL (-)	ABVD	PTCL (-)	Etoposide, etc	15	Yes	Died after 9 mo	Chang and Lee[16], 2015
59/M	CHL (+)	ABVD, PDL-1	PTCL (-)	E-CHOP, DICE, chidamide	42	Yes	Died after 7 mo	Present study

EBV: Epstein-Barr virus; CHL: Classical metachronous hodgkin lymphoma; PTCL: Peripheral T-cell lymphoma. Nd: Not done; +: Positive; -: Negative; MOPP/ABVD: Mechlorethamine, vincristine, procarbazine, prednisone/doxorubicin, bleomycin, vinblastine, dacarbazine; CHOP: Cyclophosphamide, doxorubicin, vincristine, prednisone; IVAM: Ifosfamide, etoposide, cytarabine, methotrexate; BEAM: Bendamustine, etoposide, cytarabine, melphalan; ASCT: Autologous peripheral blood stem cell transplant; IVE: Icyclophosphamide epirubicin etoposide; MTX: Methotrexate; BV: Brentuximab vedotin; E-CHOP: Etoposide CHOP; DICE: Icyclophosphamide, etoposide, cisplatin, dexamethasone; M: Male; F: Female.