Helicobacter pylori infection and peptic ulcer disease in cirrhotic patients: An updated meta-analysis

Table 1 Main characteristics of included studies in the meta-analysis

Study	Area	Study type	Peptic ulcer (Hp+/Hp-)	Prevalence	Non-ulcer (Hp+/Hp-)	Prevalence	D of Hp	D of LC
Wu et al[11], 1995	Asia	Cross-sectional	23/6	82.1%	59/32	64.8%	ELISA	Ultrosound
Kim et al[13], 2008	Asia	Cross-sectional	24/46	34.3%	76/142	34.9%	Multiple	Multiple
Siringo et al[12], 1997	Europe	Cross-sectional	39/2	95.1%	78/34	69.4%	ELISA	Multiple
Kirchner et al[10], 2011	Europe	Cross-sectional	11/7	61.1%	65/27	70.7%	ELISA	Multiple
Voulgaris et al[16], 2019	Europe	Cross-sectional	9/10	47.4%	45/36	55.6%	Multiple	Multiple
Wang et al[15], 1997	Asia	Cross-sectional	12/18	40.0%	7/12	36.8%	Multiple	Multiple
Chen et al[17], 1994	Asia	Cross-sectional	14/17	45.2%	33/44	42.9%	ELISA	Multiple
Chen et al[18], 1995	Asia	Cross-sectional	9/7	56.3%	18/16	52.9%	RUT	Multiple
Yeh et al[19], 2001	Asia	Cohort	26/19	57.8%	31/33	48.4%	UBT	Multiple
Hu et al[20], 2002	Asia	Cross-sectional	86/8	91.5%	373/189	66.4%	Multiple	Multiple
Tuo et al[21], 2000	Asia	Cross-sectional	29/45	39.2%	143/279	33.9%	Multiple	Multiple
Calvet et al[14], 1998	Europe	Cross-sectional	14/6	70.0%	79/91	46.5%	Multiple	Multiple
Zullo et al[9], 1999	Europe	Cross-sectional	51/9	85.0%	84/82	50.6%	Multiple	Multiple
Tsai[5], 1998	Asia	Cross-sectional	54/10	84.4%	46/20	69.7%	Multiple	Multiple

Cross-sectional studies (n = 13); Cohort study (n = 1). Hp: Helicobacter pylori; LC: Liver cirrhosis; UBT: Urea breath test; RUT: rapid urease test; ELISA: Enzyme linked immunosorbent assay; D: Diagnostic method.