Textural differences based on apparent diffusion coefficient maps for discriminating pT3 subclasses of rectal adenocarcinoma

Table 2 Comparison of apparent diffusion coefficient first-order textural differences between pT3a and pT3b-c stage

ADC histogram feature	pT3a (n = 30)	pT3b-c (n = 29)	P value	ICC
Mean ADC (× 10-6 mm2/s)1	879.5 ± 202.3	832.8 ± 166.7	0.339	0.906
5th ADC (× 10-6 mm2/s)1	584.4 ± 163.3	533.1 ± 111.9	0.164	0.898
10th ADC (× 10-6 mm2/s)1	638.6 ± 164.2	589.5 ± 111.0	0.183	0.901
25th ADC (× 10-6 mm2/s)1	720.2 ± 175.8	664.5 ± 125.7	0.168	0.921
90th ADC (× 10-6 mm2/s)1	1113.8 ± 275.8	1055.7 ± 229.3	0.383	0.850
Skewness1	0.24 ± 0.31	0.41 ± 0.32	0.033	0.925
Kurtosis1	0.66 ± 0.52	0.80 ± 0.70	0.376	0.909
Uniformity1	0.78 ± 0.06	0.76 ± 0.05	0.058	0.921

¹Independent samples t-test, and data are the mean ± SD.

ADC: Apparent diffusion coefficient; ICC: Intraclass correlation coefficient.