Increased morbidity and mortality of hepatocellular carcinoma patients in lower cost of living areas

Table 4 Univariate and multivariate Cox regression

	Univariate		Multivariate
	HR	95%CI	HR	95%CI
COLI ≤ 901- vs 1048-1169	1.162	1.131-1.195	1.141	1.109-1.174
COLI ≤ 901- vs 1170 ≤	1.300	1.263-1.338	1.218	1.181-1.255
COLI ≤ 901- vs 902-1044	1.130	1.099-1.163	1.067	1.037-1.097
COLI 1048-1169 vs 1170 ≤	1.118	1.085-1.001	1.067	1.035-1.100
COLI 1048-1169 vs 902-1044	0.972	0.944-1.001	0.934	0.907-0.963
COLI 1170 ≤ vs 902-1044	0.869	0.843-0.896	0.876	0.849-0.904
Age	1.014	1.013-1.015	1.012	1.011-1.013
Sex female vs male	0.903	0.881-0.926	0.925	0.901-0.950
API vs Black	0.710	0.684-0.737	0.817	0.785-0.851
API vs Hispanic	0.809	0.781-0.838	0.874	0.842-0.906
API vs Other/unknown	0.895	0.818-0.980	1.000	0.913-1.096
API vs White	0.813	0.788-0.838	0.839	0.813-0.867
Black vs Hispanic	1.139	1.100-1.180	1.069	1.031-1.108
Black vs Other/unknown	1.261	1.152-1.380	1.223	1.118-1.339
Black vs White	1.145	1.110-1.180	1.027	0.996-1.060
Hispanic vs Other/unknown	1.107	1.012-1.210	1.145	1.047-1.252
Hispanic vs White	1.005	0.978-1.032	0.961	0.935-0.988
Other/unknown vs White	0.908	0.832-0.991	0.839	0.769-0.916
Married (including common law) vs Separated/Divorced	0.839	0.814-0.865	0.909	0.881-0.937
Married (including common law) vs Single/Unmarried or domestic partner	0.799	0.779-0.820	0.876	0.852-0.901
Married (including common law) vs Unknown	0.916	0.873-0.961	1.037	0.988-1.089
Married (including common law) vs Widowed	0.708	0.683-0.733	0.881	0.847-0.915
Separated/divorced vs Single/unmarried or domestic partner	0.953	0.921-0.985	0.964	0.932- 0.998
Separated/divorced vs Unknown	1.092	1.036-1.150	1.142	1.083-1.204
Separated/divorced vs Widowed	0.843	0.809-0.879	0.969	0.927-1.013
Single/unmarried or domestic partner vs Unknown	1.146	1.090-1.205	1.184	1.125-1.247
Single/Unmarried or domestic partner vs Widowed	0.885	0.852-0.920	1.005	0.963-1.049
Unknown vs Widowed	0.773	0.731-0.817	0.849	0.801-0.899
Any Medicaid vs Insured	1.211	1.182-1.240	1.141	1.113-1.170
Any Medicaid vs Uninsured	0.705	0.670-0.741	0.830	0.789-0.874
Any Medicaid vs Unknown	0.678	0.644-0.715	0.904	0.856-0.956
Insured vs Uninsured	0.582	0.555-0.611	0.728	0.693-0.764
Insured vs Unknown	0.560	0.533-0.589	0.792	0.751-0.836
Uninsured vs Unknown	0.962	0.900-1.029	1.089	1.016-1.168
Stage I vs II	0.938	0.907-0.970	0.833	0.805-0.862
Stage I vs III	0.373	0.363-0.385	0.570	0.552-0.590
Stage I vs IV	0.221	0.214-0.229	0.372	0.359-0.386
Stage vs Unknown	0.370	0.359-0.382	0.656	0.632-0.681
Stage II vs III	0.398	0.385-0.412	0.685	0.658-0.713
Stage II vs IV	0.236	0.227-0.245	0.447	0.429-0.466
Stage II vs Unknown	0.395	0.381-0.409	0.788	0.754-0.823
Stage III vs IV	0.593	0.574-0.613	0.653	0.631-0.675
Stage III vs Unknown	0.992	0.961-1.024	1.151	1.108-1.196
Stage IV vs Unknown	1.673	1.6161.732	1.763	1.699-1.830
20 vs 21-30	0.796	0.758-0.835	0.835	0.796-0.876
20 vs 31-50	0.564	0.540-0.590	0.672	0.643-0.703
20 vs 50+	0.308	0.296-0.321	0.506	0.484-0.529
20 vs Unknown	0.235	0.225-0245	0.454	0.432-0.476
21-30 vs 31-50	0.710	0.683-0.737	0.805	0.774-0.837
21-30 vs 50+	0.387	0.374-0.401	0.606	0.582-0.630
21-30 vs Unknown	0.295	0.284-0.306	0.543	0.520-0.568
31-50 vs 50+	0.546	0.530-0.562	0.753	0.728- 0.778
31-50 vs Unknown	0.416	0.403-0.430	0.675	0.650-0.701
50+ vs Unknown	0.763	0.742-0.783	0.897	0.869-0.926
LRT	2.184	2.099-2.273	1.931	1.852-2.012
Resection	2.670	2.548-2.799	2.986	2.845-3.135
Transplant	6.311	5.837-6.822	5.352	4.941-5.796
2007-2009 vs 2010-2012	1.071	1.044-1.098	1.074	1.048-1.102
2007-2009 vs 2013-2015	1.153	1.123-1.184	1.143	1.113-1.174
2010-2012 vs 2013-2015	1.077	1.050-1.104	1.064	1.037-1.091

Bold indicates nonsignificant confidence interval. API: Asians and Pacific Islanders; CI: Confidence interval; COLI: Cost of living index; HR: Hazard ratio; LRT: Locoregional therapy.