Diagnostic and prognostic value of secreted protein acidic and rich in cysteine in the diffuse large B-cell lymphoma

Figure 3 Diagnostic value of secreted protein acidic and rich in cysteine in diffuse large B-cell lymphoma. A: The mRNA level of secreted protein acidic and rich in cysteine (SPARC) was confirmed with The Cancer Genome Atlas (TCGA)-diffuse large B-cell lymphoma (DLBCL) database (^aP < 0.001 vs control group); B: The receiver operating characteristic (ROC) analysis was conducted with the TCGA-DLBCL database; C: The validation datasets including the Compagno and Brune DLBCL datasets were adopted to validate the SPARC expression (^aP < 0.001 vs control group); D: The ROC analysis was performed to evaluate the diagnostic value of SPARC for the DLBCL. ^aP < 0.001 was considered statistical difference. AUC: Area under curve; CI: Confidence interval; TPR: True positive rate.