Effect of exercise training on left ventricular remodeling in patients with myocardial infarction and possible mechanisms

Table 6 Comparison of matrix metalloproteinase-9, tissue inhibitor of metalloproteinases-1, and matrix metalloproteinase-9/tissue inhibitor of metalloproteinases-1 ratio in rehabilitation exercise and control groups at different time points

Items	Time	Rehabilitation exercise group (n = 30)	Control group (n = 30)
MMP-9 (ng/mL)	Immediately	6.7 ± 2.97	6.8 ± 3.12
	Days 10-14	8.2 ± 2.5	8.1 ± 2.55
	Day 30	4.2 ± 1.88	5.0 ± 1.98a
	6 mo	4.0 ± 1.87	5.1 ± 2.02a
TIMP-1 (ng/mL)	Immediately	2.1 ± 0.52	2.1 ± 0.51
	Days 10-14	2.4 ± 0.71	2.5 ± 0.65
	Day 30	2.8 ± 0.67	3.0 ± 0.55a
	6 mo	2.7 ± 0.56	2.98 ± 0.51a
MMP-9/TIMP-1	Immediately	3.05 ± 1.05	2.98 ± 1.03
	Days 10-14	4.21 ± 1.58	4.11 ± 1.44
	Day 30	1.78 ± 0.88	1.25 ± 0.66a
	6 mo	1.58 ± 0.67	1.22 ± 0.58a

Intergroup comparison.

^aP < 0.05. MMP-9: Matrix metalloproteinase-9; TIMP-1: Tissue inhibitor of metalloproteinases-1.