Risk factors for preoperative carcinogenesis of bile duct cysts in adults

Table 5 Clinical data of ten bile duct cyst patients with dysplasia or carcinoma

No.	Sex	Age (yr)	Todani type	Operation	Lesion location	Pathology	TNM stage1	Follow-up time (mo)	Outcome
1	F	39	IVa	CH + CE + HJ	Cyst	Mucinous adenocarcinoma	T4N0M0	40	Recurred 10 mo after surgery, alive with tumor
2	F	46	IVa	CH + CE + HJ	Gallbladder	Mucinous adenocarcinoma	T3N0M0	6	Survived disease free for 6 mo after surgery, then lost to follow-up
3	F	44	IVa	CH + CE + HJ	Cyst	Moderate dysplasia	--	52	Disease-free survival
4	F	26	IVa	CH + CE + HJ	Cyst + gallbladder	Mild dysplasia	--	53	Disease-free survival
5	F	61	I	CH + CE + HJ	Gallbladder	Adenocarcinoma	T2N0M0	40	Disease-free survival
6	F	27	IVa	CH + CE + HJ	Cyst + gallbladder	Moderate dysplasia	--	66	Disease-free survival
7	F	33	IVa	Pancreaticoduodenectomy	Cyst	Adenocarcinoma	TisN0M0	81	Disease-free survival
8	F	18	I	CH + CE + HJ	Cyst + gallbladder	Mild dysplasia	--	40	Disease-free survival
9	F	65	I	CH + CE + HJ	Gallbladder	Adenocarcinoma	T1N0M0	65	Disease-free survival
10	F	22	IVa	CH + CE + HJ	Cyst	Mild dysplasia	--	--	Lost to follow-up

¹Staging was according to the American Joint Committee on Cancer 8^th 2018 Tumor Node Metastasis classification.

CH: Cholecystectomy; CE: Cyst excision; HJ: Hepaticojejunostomy; TNM: Tumor node metastasis.