Effects of perioperative rosuvastatin on postoperative delirium in elderly patients: A randomized, double-blind, and placebo-controlled trial

Table 1 Demographic and baseline characteristics of the study population

Group	Place group	Rosuvastatin group	P value
Number of patients	411	410
Age (mean ± SD)	66.5 ± 5.3	66.3 ± 5.1	0.664
Gender, n (%)			0.243
Male	186(45.3)	169 (41.2)
Female	225 (54.7)	241 (58.8)
History of hypertension, n (%)			0.623
Yes	109 (26.5)	115 (28.0)
No	302 (73.5)	295 (72)
History of diabetes, n (%)			0.558
Yes	88 (21.4)	81 (19.8)
No	323 (78.6)	329 (80.2)
Nicotine use, n (%)			0.518
Yes	72 (17.5)	79 (19.3)
No	339 (82.5)	331 (80.7)
Type of surgery, n (%)			> 0.05
Thoracic operation	77 (18.7)	69 (16.8)
Abdominal operation	93 (22.6)	105 (25.6)
Orthopedic operation	158 (38.4)	142 (34.6)
Gynecological operation	44 (10.7)	58 (14.4)
Others	39 (9.6)	36 (8.6)
Duration of anesthesia (min)	114.0 ± 42.7	115.5 ± 42.2	0.625
Blood transfusion during surgery, n (%)			0.660
Yes	48 (11.7)	52 (12.7)
No	363 (88.3)	358 (87.3)
Intraoperative medication, n (%)			> 0.05
Midazolam
Fentanyl	411 (100)	410 (100)
Propofol	411 (100)	410 (100)
Atropine	75 (18.2)	79 (19.3)
Postoperative analgesics (7 d), n (%)			> 0.05
Diclofenac sodium	104 (25.3)	99 (24.1)
Morphine	85 (20.7)	91 (22.2)
Midazolam	41 (10.0)	57 (13.9)
No	181 (44.0)	163 (39.8)