Therapeutic plasma exchange for hyperlipidemic pancreatitis: Current evidence and unmet needs

Table 1 Reports comparing triglyceride clearance rate and mortality between therapeutic plasma exchange and nontherapeutic plasma exchange groups

Ref.	Year	Study design	Study size	TPE vs Non-TPE	24 h TG clearance rate	Mortality
Yu et al[12]	2020	Retrospective study	132	43 with TPE; 46 with IIT; 43 with NIIT	TPE: 71.00%; IIT: 68.00%; NIIT: 62.00%	TPE: 6.89%; IIT: 6.52%; NIIT: 2.00%
Fei et al[32]	2020	Retrospective study	8	All with TPE	60.30%	/
Gubensek et al[22]	2014	Retrospective cohort study	103	74 with early TPE; 29 with late TPE (conservative treatment followed by TPE)	Early TPE: 59%; Conservative treatment: 27%	Early TPE: 7%; Late TPE: 6%
Yildirim Şimşir et al[33]	2019	Retrospective study	31	All with TPE	69.70%	0
Kandemir et al[47]	2018	Retrospective study	33	All with TPE	54.40%	3.00%
Miyamoto et al[35]	2017	Retrospective study	30	10 with TPE; 20 without TPE	No difference between groups	TPE: 0%; Non-TPE: 10%
Biberci Keskin et al[39]	2019	Retrospective study	41	12 with TPE; 29 without TPE	TPE: 44%; Non-TPE: /	TPE: 25%; Non-TPE: 0

TG: Triglycerides; TPE: Therapeutic plasma exchange; IIT: Insulin intensive therapy; NIIT: Non-insulin intensive therapy.