Role of ranulas in early diagnosis of Sjögren’s syndrome: A case report

Table 1 Laboratory parameters of the patient with primary Sjögren’s syndrome who had a ranula before

Laboratory parameters	Day 1 (March 1 on outpatient service)	After 2 wk of treatment	After 3 mo of treatment	After 6 mo of treatment	After one year and three mo of treatment
WBC (× 109/L)	3.42↓	3.97	4.25	4.79	4.25
Neutrophils, %	49.1↓	55.8	55.6	60.2	55.6
Lymphocytes, %	43.3↑	35.7	36.6	31.9	36.6
ESR (mm/h)	33↑	17	10	17	7
ALT (U/L)	23	18	17	13	24
AST (U/L)	31	23	27	24	29
Creatinine (μmol/L)	67	66	86	76	68
EGFR (mL/min)	110.5	112.5	81.7	94.2	107.8
ANA	1:320	-	-	1:320	1:320
Anti-dsDNA antibody	Negative	-	-	Negative	Negative
Anti-RNP/Sm antibody	Negative	-	-	Negative	Negative
Anti-Sm antibody	Negative	-	-	Negative	Negative
Anti-SSA antibody	Positive	-	-	Positive	Positive
Anti-SSB antibody	Positive	-	-	Positive	Positive
IgA (g/L)	1.60	-	-	1.66	1.57
IgG (g/L)	20.10↑	-	-	15.9↑	14.47
IgM (g/L)	1.15	-	-	1.00	1.08
C3 (g/L)	0.69↓	-	-	0.75↓	1.05
C4 (g/L)	0.18	-	-	0.19	0.26
RF (IU/mL)	441↑	-	-	165↑	46.86↑

WBC: White blood cells; ESR: Erythrocyte sedimentation rate; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; EGFR: Estimate glomerular filtration rate; ANA: Anti-nuclear antibody; dsDNA: Double-stranded DNA; RNP: Ribonucleoprotein; SSA: Sjögren’s syndrome–related antigen A; SSB: Sjögren’s syndrome–related antigen B; Ig: Immunoglobulin; C3: Complement component 3; C4: Complement component 4; RF: Rheumatoid factor.