Giant androgen-producing adrenocortical carcinoma with atrial flutter: A case report and review of the literature

Table 1 Pre- and post-operative hormone levels and echocardiography

	Preoperative	Postoperative			Normal range
		1-d	3-mo	6-mo
Hormone
Total testosterone (nmol/L)	8.42-10.11	1.77			0.22-2.9
DHEAS (μg/dL)	864.2-1492	31		< 0.1	9.4-246.0
Cortisol (μg/dL): a.m.	-	11.8	31.3	3.2	3.7-19.4
Cortisol (μg/dL): p.m.	24.1	-	-	-	2.9-17.3
Androstenedione (ng/mL)	> 10				< 2.11
17-OH progesterone (ng/mL)	> 251	1.85			0.2-0.9
Urinary metanephrines (μg/24 h)	49.8				25-312
FT4 (ng/dL)	1.13	1.55			0.89-1.76
FT3 (pg/mL)	2.64				2.2-5
TSH (μUI/mL)	3.46				0.4-4
Peptide C	8.53				0.9-7.1
Glucagon (ng/L)	207				< 209
FSH (mIU/mL)	< 10				21.7-153
LH (mIU/mL)	< 10				11.3-39.8
PTH (pg/mL)	32.46				15-63
Echocardiography
Left atrium dimension (cm)	45			44	3.0-4.0
Left atrium volume/index (mL/m2)	57/33			56/33	22 ± 6
Left ventricle dimension (cm)	60			45	4.2-5.9
Estimated ejection fraction (%)	28			57	50-80
Estimated pulmonary artery pressure (mmHg)	46			20	9-18

DHEAS: Dehydroepiandrosterone sulfate; FSH: Follicle-stimulating hormone; FT3: Triiodothyronine; FT4: Thyroxine; TSH: Thyrotropin; LH: Luteinizing hormone; PTH: Parathyroid hormone.