Perioperative mortality of metastatic spinal disease with unknown primary: A case report and review of literature

Table 1 Abnormal findings from laboratory and pathological examinations

Examination	Result	Content
Serum tumor marker	Increased	CA19-9
	Normal	AFP, CA125, CA242, CEA, CYFRA 21-1, NSE, PSA, SCCA
Needle biopsy	Diffusely positive	Vimentin
	Partially positive	EMA, NSE, CK7, CK18, CK (AE1/AE3)
	Negative	AFP, CD31, CD34, CgA, CK20, HepPar-1, HMB45, Melan-A, Napsin, S-100, SMA, Syn, TTF-1
Postoperative pathology	Diffusely positive	Vimentin, Cam5.2
	Partially positive	CK5/6, CK (AE1/AE3), CD10, EMA, Ki-67 (30%)
	Negative	CD31, CD34, CD68, CD163, Desmin, HMB45, S-100, SMA

AFP: Alpha-fetoprotein; CA: Carbohydrate antigen; CD: Clusters of differentiation; CEA: Carcinoembryonic antigen; CgA: Glycoprotein hormones; CK: Cytokeratin; CYFRA 21-1: Cytokeratin fragment antigen 21-1; EMA: Epithelial membrane antigen; HMB45: Human melanoma black 45; NSE: Neuron-specific enolase; PSA: Prostate-specific antigen; SCCA: Squamous cell carcinoma antigen; SMA: Smooth muscle actin; Syn: Synaptophysin; TTF-1: Thyroid transcription factor 1.