Severe hyperbilirubinemia in a neonate with hereditary spherocytosis due to a de novo ankyrin mutation: A case report

Figure 1 The representative clinical characteristics, imaging findings, and peripheral blood smears results. A: The dynamic changes of serum bilirubin (SBR) (blue) and hemoglobin (HB) (orange) levels during hospitalization. The treatment of exchange transfusion and plasmapheresis are indicated by the black and red arrow respectively. The number on the X axis represents the number of days after birth; B: The imaging finding of axial T1-weighted brain magnetic resonance imaging sequence done at 1 wk after birth; C: Morphology of erythrocytes in the blood smear (Wright-Giemsa stain; magnification, × 1000). The spherocyte is indicated by the orange arrows.