Early diagnosis, treatment, and outcomes of five patients with acute thallium poisoning

Table 3 Interval from exposure to diagnosis and treatments of five patients with acute thallium poisoning

Patient No.	Interval from exposure to diagnosis (d)	Time of receiving treatments after exposure				Duration of PB treatment (d)	Urine thallium concentration (µg/L)		Blood thallium concentration (µg/L)
		Sodium thiosulfate	DMPS	HP	PB		Before treatment	After treatment	Before treatment	After treatment
1	9	3rd day	12th day	15th day	15th day	14	7200	160	280	0
2	8	3rd day	10th day	10th day	11th day	15	5100	130	210	0
3	11	10th day	11th day	15th day	15th day	15	250	0	150	0
4	12	11th day	11th day	15th day	15th day	14	370	0	40	0
5	12	11th day	11th day	15th day	15th day	16	580	0	46	0

The urine and blood samples were successively sent to Hospital 307 of Chinese People’s Liberation Army to confirm the diagnosis of acute thallium poisoning. The day when the patients underwent detoxification treatments after exposure is listed in the table. The Prussian blue (PB) treatment was implemented in Hospital 307 of Chinese People’s Liberation Army and lasted for 14 to 16 d. The urine and blood thallium concentration before and after PB treatment was recorded. Sodium thiosulfate: 0.64 g, intravenous injection per day; DMPS: Dimercaptopropane sulfonate 0.25 g, intramuscular injection twice daily; HP: Hemoperfusion; PB: Prussian blue 3.3 g in mannitol 50 mL, orally four times daily.