Splenic Kaposi’s sarcoma in a human immunodeficiency virus-negative patient: A case report

Figure 4 Hematoxylin and eosin staining and immunohistochemistry. A: Multinodular tumors with a clear boundary and composed of proliferative spindle cells with interstitial hemorrhage (× 10); B: Proliferating spindle cells divided by slit-like spaces containing red blood cells, which were sieve-like or beehive in shape, and eosinophilic hyaline bodies scattered in the cytoplasm or extracellular of spindle cells (× 200); C: Immunohistochemical staining was positive for CD31, revealing splenic Kaposi’s sarcoma (KS) (× 200); D: Immunohistochemical staining was positive for CD34, revealing splenic KS (× 200); E: Immunohistochemical staining was positive for ERG (× 200); F: Immunohistochemical staining was positive for FLI-1 (× 200).