Evaluation of a five-gene signature associated with stromal infiltration for diffuse large B-cell lymphoma

Figure 6 The five hub genes were closely associated with infiltration level of cancer-associated fibroblasts with the MCP-Counter method. A-E: The alpha-2-macroglobulin (A2M) (A), cathepsin B (CTSB) (B), fibronectin (FN1) (C), matrix metallopeptidase 9 (MMP9) (D), and secreted protein acidic and cysteine-rich (SPARC) (E) gene expressions were evaluated for correlation with infiltration levels of cancer-associated fibroblasts (CAFs) in diffuse large B-cell lymphoma, and the correlation analysis was conducted with the Spearman method. P < 0.05 was considered as statistically different.