Evaluation of a five-gene signature associated with stromal infiltration for diffuse large B-cell lymphoma

Figure 2 The five hub genes were confirmed as overexpressed in diffuse large B-cell lymphoma. A: The protein-protein interaction was confirmed in STRING, and the hub genes were obtained; B-F: The expressions of alpha-2-macroglobulin (A2M) (B), fibronectin (FN1) (C), secreted protein acidic and cysteine-rich (SPARC) (D), cathepsin B (CTSB) (E), and matrix metallopeptidase 9 (MMP9) (F) were subjected to GEPIA to analyze the expression in diffuse large B-cell lymphoma and normal lymphocytes within The Cancer Gene Atlas dataset. ^aP < 0.001 vs the diffuse large B-cell lymphoma tumor samples.