Botulinum toxin injection for Cockayne syndrome with muscle spasticity over bilateral lower limbs: A case report

Table 1 Results of the assessments at different periods after the botulinum toxin A injection

Outcome measures		Date
		Pre-injection	Post-injection week 1	Post-injection week 2	Post-injection week 4	Post-injection week 8	Post-injection week 12
MAS (0-4)	Plantar flexors	R: 3	R: 2	R: 2	R: 2	R: 2	R: 3
		L: 3	L: 2	L: 2	L: 2	L: 2	L: 3
	Foot invertors	R: 3	R: 2	R: 2	R: 2	R: 2	R: 3
		L: 3	L: 2	L: 2	L: 2	L: 2	L: 3
PROM	Ankle plantar flexion	R: 45°-50°	R: 35°-50°	R: 35°-50°	R: 35°-50°	R: 35°-50°	R: 45°-50°
		L: 40°-50°	L: 30°-50°	L: 30°-50°	L: 30°-50°	L: 30°-50°	L: 40°-50°
	Inversion	R: 50°-60°	R: 40°-60°	R: 40°-60°	R: 40°-60°	R: 40°-60°	R: 50°-60°
		L: 45°-60°	L: 35°-60°	L: 35°-60°	L: 35°-60°	L: 35°-60°	L: 45°-60°
FPS-R		6	4	4	4	4	4
SARA		15	14	14	14	14	15

MAS: Modified Ashworth scale; PROM: Passive range of motion; R: Right; L: Left; SARA: Scale for the Assessment and Rating of Ataxia; FPS-R: Faces Pain Scale-Revised.