AWGS2019 vs EWGSOP2 for diagnosing sarcopenia to predict long-term prognosis in Chinese patients with gastric cancer after radical gastrectomy

Table 2 Univariate and multivariate analyses for predictors of disease-free survival

Factor	Univariable analysis		Multivariate analysis
			AWGS2019		EWGSOP2
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
AWGS2019	3.311 (2.470-4.439)	0.001b	2.150 (1.547-2.988)	0.001b
EWGSOP2	2.566 (1.803-3.651)	0.001b			1.599 (1.092-2.339)	0.016a
Age	1.036 (1.021-1.051)	0.001b
Gender
Male/female	1.038 (0.745-1.448)	0.824
BMI	0.934 (0.890-0.980)	0.005b
Albumin	0.930 (0.904-0.957)	0.001b
Hypertension
Yes/No	1.290 (0.948-1.755)	0.105
Diabetes
Yes/No	0.765 (0.476-1.229)	0.268
ASA grade
II/I	1.301 (0.773-2.190)	0.323
III/I	2.402 (1.366-4.225)	0.002b
CCI	1.288 (1.146-1.448)	0.001b
Operative duration	1.003 (1.001-1.006)	0.017a
TNM stage
II/I	2.494 (1.349-4.610)	0.004b	1.660 (0.887-3.108)	0.113	1.636 (0.872-3.067)	0.125
III/I	8.093 (4.825-13.574)	0.001b	4.751 (2.753-8.200)	0.001b	4.968 (2.876-8.582)	0.001b
Laparoscopic surgery
Yes/No	0.463 (0.306-0.700)	0.001b
Type of resection
Total/Subtotal	1.864 (1.400-2.481)	0.001b
Anastomosis method
B2/B1	2.571 (1.672-3.954)	0.001b	1.414 (0.904-2.210)	0.129	1.423 (0.911-2.223)	0.122
RouY/B1	2.747 (1.920-3.390)	0.001b	1.614 (1.109-2.348)	0.012a	1.600 (1.100-2.328)	0.014a
Lymph node dissection
D2/D1	1.036 (0.693-1.548)	0.864
Histologic type
Undifferentiated/differentiated	2.756 (1.855-4.095)	0.001b	1.899 (1.263-2.856)	0.002b	1.972 (1.309-2.970)	0.001b
Total complications	1.678 (1.221-2.307)	0.001b
Pneumonia	2.574 (1.601-4.137)	0.001b	1.990 (1.222-3.241)	0.006b	1.935 (1.184-3.163)	0.008b
Leakage	3.325 (1.757-6.292)	0.001b	3.018 (1.557-5.853)	0.001b	3.339 (1.722-6.476)	0.001b
Wound infection	1.171 (0.435-3.153)	0.755
Intestinal obstruction	2.159 (0.888-5.252)	0.090
Gastrointestinal dysfunction	0.982 (0.484-1.994)	0.960
Intra-abdominal infection	1.410 (0.767-2.594)	0.269
Intra-abdominal hemorrhage	0.888 (0.365-2.160)	0.794
Venous thrombosis	0.997 (0.410-2.425)	0.995
First time to Flatus	1.101 (1.050-1.154)	0.001b
Hospital stay	1.026 (1.017-1.035)	0.001b
Readmission within 30 d	1.601 (0.929-2.759)	0.090

^aP < 0.05.

^bP < 0.01. BMI: Body mass index; CCI: Charlson comorbidity index; ASA: American Society of Anesthesiologists; HR: Hazard ratio; CI: Confidence interval.