Why MUC16 mutations lead to a better prognosis: A study based on The Cancer Genome Atlas gastric cancer cohort

Figure 3 Differentially expressed genes and drug sensitivity. A: Volcano plot showing differentially expressed genes between the MUC16 mutation group and the MUC16 wild-type group, up-regulated genes are in red, down-regulated genes are in green, and black represents genes that are not differentially expressed; B: Error rate for the data as a function of the classification tree and out-of-bag importance values for the predictors; C: Genes of relative importance greater than 0.65; D: The plot showing the correlation between NPY1R expression and the sensitivity of gastric cancer cell lines to various drugs, with the three most negatively correlated drugs being WH-4-023, WZ-184, and Roscovitine. NPY1R: Neuropeptide Y receptor Y1.