Fulminant amebic colitis in a patient with concomitant cytomegalovirus infection after systemic steroid therapy: A case report

Figure 3 Macroscopic and histopathological findings during autopsy of a 68-year-old man who died after intestinal perforation. A: Macroscopic findings revealing transmural intestinal necrosis and a “ragged appearance” in the rectum, descending colon, and sigmoid colon; B: Histopathological findings showing full-thickness necrosis of the intestinal wall from the mucosa to the serosa. Furthermore, severe infiltration of the necrotic tissue with ameba is visible (hematoxylin and eosin stain, × 4); C: A few intranuclear cytomegalovirus inclusions can be detected on immunohistochemical examination of the sigmoid colon (arrow, × 40); D: Entamoeba histolytica trophozoites are visible in the submucosa (periodic acid–Schiff stain, arrow, × 20).