Sarcomatoid carcinoma of the pancreas — a rare tumor with an uncommon presentation and course: A case report and review of literature

Figure 2 Histological examination and immunohistochemical staining. A and B: Histological examination of the pancreatic neoplasm reveals infiltration by malignant cells displaying a glandular and spindle-cell pattern. Hematoxylin and eosin, 4 × (A); Hematoxylin and eosin, 10 × (B). Glandular component lined by atypical epithelium and sarcomatous spindle cell component with pleomorphic giant cells; C: Immunohistochemical staining for pan-cytokeratin, 10 × (C). Glandular and sarcomatoid components are positive for this epithelial marker; D: Immunohistochemical stain for vimentin, 10 × (D). Vimentin is the most common mesenchymal marker. The epithelial glandular component is negative, and the sarcomatoid component is strongly positive.