Paget’s disease of bone: Report of 11 cases

Table 2 Medical treatment and follow-up for the 11 patients with Paget’s disease of bone

	Medical treatment	Follow-up	Symptoms	ALP (posttreatment IU/L)
1	NA	1 yr	No symptom	NA
2	Three cycles of etidronate sodium 200 mg administered twice a day orally for 2 wk and withdrawn for 11 wk	10 yr	Bone pain relieved; mobility of the affected limb improved after surgery	311
3	Pamidronate bisphosphonate 15 mg/week intravenous injection for 7 wk	3 mo	Bone pain relieved	1398
4	Three cycles of etidronate sodium 200 mg administered twice a day orally for 2 wk and withdrawn for 11 wk	19 yr	Bone pain relieved	212
5	Alendronate 10 mg once a day orally for 7 mo	15 yr	Bone pain relieved	158
6	Pamidronate bisphosphonate 15 mg/week intravenous injection for 7 wk	3 yr	Bone pain relieved	245
7	Alendronate 10 mg once a day orally for 7 mo	3 yr	Bone pain relieved	752
8	Zoledronate 5 mg per year intravenous injection for 3 yr	5 yr	Bone pain relieved	977
9	Zoledronate 5 mg per year intravenous injection for 3 yr	3 yr	Bone pain relieved	60
10	Zoledronate 5 mg per year intravenous injection for 2 yr	2 yr	Bone pain relieved	52
11	Pamidronate bisphosphonate 15 mg/week intravenous injection for 7 wk	1 yr	No symptom	405

ALP: Alkaline phosphatase; NA: Not available.