Comparison of smear cytology with liquid-based cytology in pancreatic lesions: A systematic review and meta-analysis

Table 3 Meta-regression analysis of sensitivity of liquid-based cytology

Parameter	Category	Studies, n	Sensitivity	P value
Type	Prospective	7	0.75 (0.67-0.84)	0.12
	Retrospective	3	0.75 (0.63-0.87)
Subject	≥ 50	8	0.77 (0.70-0.83)	0.85
	< 50	2	0.68 (0.46-0.89)
Match	Homology	9	0.74 (0.67-0.80)	0.01
	Heterology	1	0.90 (0.80-1.00)
ROSE	Without ROSE	8	0.79 (0.73-0.84)	0.80
	With ROSE	2	0.60 (0.44-0.76)
LBC	TP	5	0.70 (0.61-0.80)	0.00
	SP/CP	5	0.80 (0.73-0.88)
Classification	Common	5	0.74 (0.64-0.85)	0.05
	Others1	5	0.76 (0.67-0.85)

¹Includes common cytological diagnosis classification methods that lack adequate cytological samples; these samples were excluded from the final analysis.

CP: Cell prep plus; LBC: Liquid-based cytology; ROSE: Rapid On-Site Evaluation; SP: Sure path; TP: Thin prep.