Comparison of smear cytology with liquid-based cytology in pancreatic lesions: A systematic review and meta-analysis

Table 2 Meta-regression analysis of sensitivity of smear cytology

Parameter	Category	Studies, n	Sensitivity	P value
Type	Prospective	7	0.83 (0.74-0.92)	0.71
	Retrospective	3	0.65 (0.47-0.84)
Subject	≥ 50	8	0.78 (0.68-0.89)	0.67
	< 50	2	0.80 (0.56-1.00)
Match	Homology	9	0.80 (0.70-0.89)	0.48
	Heterology	1	0.64 (0.27-1.00)
ROSE	Without ROSE	8	0.74 (0.64-0.85)	0.03
	With ROSE	2	0.90 (0.80-1.00)
LBC	TP	5	0.83 (0.72-0.94)	0.87
	SP/CP	5	0.73 (0.58-0.88)
Classification	Common	5	0.86 (0.77-0.95)	0.94
	Other1	5	0.71 (0.58-0.84)

¹Includes common cytological diagnosis classification methods that lack adequate cytological samples; these samples were excluded from the final analysis.

CP: Cell prep plus; LBC: Liquid-based cytology; ROSE: Rapid On-Site Evaluation; SP: Sure path; TP: Thin prep.