Pulmonary arterial hypertension in a patient with hereditary hemorrhagic telangiectasia and family gene analysis: A case report

Figure 3 Pedigree chart for the proband and her family. The black arrow indicates the proband. The black triangles (▲) represent family members (α, β, γ, δ, ε, and ζ) who completed the mutation analysis of whole exons. The pluses (+) represent members who showed positivity for the gene mutation, that is, existence of the ACVRL1 mutation (c. 1232G>A, p. Arg411Gln). The minus (-) represents the member who showed negativity for the gene mutation.