Comprehensive clinicopathologic characteristics of intraabdominal neurogenic tumors: Single institution experience

Figure 2 Histopathology of Schwann cell hamartoma and malignant peripheral sheet tumor. A: Low (inset) and high power view of mucosal Schwann cell hamartoma located in sigmoid colon [hematoxylin and eosin (H&E), × 40 and × 100, respectively]; B: Mucosal Schwann cell hamartoma: Benign mucosal proliferation of Schwann cells filling and expanding the lamina propria with poorly circumscribed margins (H&E, × 200); inset: diffuse S100 positivity supporting the Schwannian origin (immunohistochemistry, × 100); C: Malignant peripheral nerve sheet tumor with broad geographic necrosis (H&E, × 100); D: Prominent cellular pleomorphism (H&E, × 400) and frequent mitosis and apoptotic bodies seen in malignant peripheral nerve sheet tumor (inset: H&E, × 400).