Epidemiological and clinical characteristics of 65 hospitalized patients with COVID-19 in Liaoning, China

Table 2 Radiological and laboratory findings of hospitalized patients with coronavirus disease 2019

	Normal range	Total (n = 65)	Nonsevere (n = 49)	Severe (n = 16)	P value
Chest CT findings, n (%)
Bilateral distribution	NA	53 (81.5)	37 (75.5)	16 (100)	0.069
Pure ground-glass opacity	NA	24 (36.9)	23 (46.9)	1 (6.3)	0.003
Ground-glass opacity and Consolidation	NA	41 (63.1)	26 (53.1)	15 (93.8)	0.003
Peripheral distribution	NA	65 (100)	49 (100)	16 (100)	NA
Peripheral and central distribution	NA	26 (40)	17 (34.7)	9 (56.3)	0.126
Laboratory findings
White blood cell count, × 109/L	3.5-9.5	5 (3.47-6.75)	5 (3.47-6.8)	5.01 (3.59-5.51)	0.976
Neutrophil count, × 109/L	1.8-6.3	3.71 ± 2.58	3.26 ± 1.59	5.1 ± 4.2	0.104
Lymphocyte count, × 109/L	1.1-3.2	1.15 (0.83-1.78)	1.3 (0.9-1.95)	0.82 (0.44-1.08)	< 0.001
< 1.0, n (%)	NA	26 (40)	15 (30.6)	11 (68.8)	0.007
Monocyte count, × 109/L	0.1-0.6	0.41 (0.3-0.41)	0.4 (0.35-0.47)	0.4 (0.3-0.4)	0.253
Platelet count, × 109/L	125-350	200 ± 72	204 ± 79	188 ± 47	0.445
Prothrombin time, s	11-14	11.58 (10.5-12)	11.5 (10.5-11.6)	11.5 (10.4-12.2)	0.788
D-dimer, mg/L	0-0.55	0.27 (0.18-0.44)	0.27 (0.16-0.27)	0.51 (0.27-0.81)	< 0.001
Albumin, g/L	35-50	35.6 ± 5.5	36.2 ± 5.2	33.6 ± 6.1	0.099
Alanine aminotransferase, U/L	0-40	29 (19.5-48.5)	29 (17-40)	41.5 (21.8-69.3)	0.068
Aspartate aminotransferase, U/L	0-40	25 (20-31)	25 (17-29)	27.5 (22.3-43.5)	0.105
Total bilirubin, mmol/L	3-22	18.5 ± 6.6	17.7 ± 6.1	21.1 ± 7.7	0.08
Creatinine, μmol/L	58-110	56.8 ± 13.8	56.6 ± 14.4	57.4 ± 12.2	0.843
Blood urea nitrogen, mmol/L	2.5-6.1	3.7 ± 1.1	3.6 ± 0.9	4.2 ± 1.3	0.046
Creatine kinase, U/L	55-170	50 (35-79)	50 (32.5-62.5)	74 (48.3-130)	0.03
Creatine kinase-MB, U/L	0-16	2 (1-6.5)	2 (1-4)	5.5 (2-12.1)	0.015
Lactate dehydrogenase, U/L	313-618	461 (407-614)	450 (386-479)	707 (592-980)	< 0.001
> 618, n (%)	NA	16 (24.6)	4 (8.2)	12 (75)	< 0.001
Potassium, mmol/L	3.5-5.1	4.1 ± 0.5	4.3 ± 0.5	3.8 ± 0.5	0.001
Sodium, mmol/L	137-145	134 ± 3.5	135 ± 3.1	132 ± 3.8	0.002
C-reactive protein, mg/L	0-8	6.2 (2.9-28.7)	6.1 (1.5-7.2)	52 (12.7-100.8)	< 0.001
> 8, n (%)	NA	21 (32.3)	9 (18.4)	12 (75)	< 0.001
Procalcitonin, ng/mL	0-0.25	0.04 (0.04-0.05)	0.04 (0.04-0.05)	0.043 (0.04-0.08)	0.084
Duration of viral shedding after COVID-19 onset	NA	19.5 (17-24)	19.5 (16-21)	23.5 (19.6-30.3)	0.001

CT: Computed tomography; COVID-19: Coronavirus disease 2019; NA: Not applicable.