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©The Author(s) 2021.
World J Clin Cases. Apr 6, 2021; 9(10): 2192-2204
Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2192
Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2192
Table 1 Characteristics of the patients
| Clinicopathological factor | Total (n = 42) | Lymph node metastasis | Residual tumor | ||||
| No (n = 37) | Yes (n = 5) | P value | No (n = 29) | Yes (n = 13) | P value | ||
| Age (yr), n (%) | 0.926 | 0.513 | |||||
| < 60 | 16 (38.1) | 14 (37.8) | 2 (40.0) | 12 (41.4) | 4 (30.8) | ||
| ≥ 60 | 26 (61.9) | 23 (62.2) | 3 (60.0) | 17 (58.6) | 9 (69.2) | ||
| Sex (male), n (%) | 35 (83.3) | 34 (91.9) | 1 (20.0) | < 0.001 | 26 (89.7) | 9 (69.2) | 0.101 |
| Tumor location, n (%) | 0.316 | 0.360 | |||||
| Upper stomach | 12 (28.6) | 12 (32.4) | 0 (0) | 9 (31.0) | 3 (23.1) | ||
| Middle stomach | 17 (40.5) | 14 (37.9) | 3 (60.0) | 13 (44.8) | 4 (30.8) | ||
| Lower stomach | 13 (30.9) | 11 (29.7) | 2 (40.0) | 7 (24.2) | 6 (46.1) | ||
| Tumor size (cm), n (%) | 0.281 | 0.862 | |||||
| < 2 | 9 (21.4) | 7 (18.9) | 2 (40.0) | 6 (20.7) | 3 (23.1) | ||
| ≥ 2 | 33 (78.6) | 30 (81.1) | 3 (60.0) | 23 (79.3) | 10 (76.9) | ||
| Gross type, n (%) | 0.207 | 0.106 | |||||
| Protruded | 8 (19) | 8 (21.6) | 0 (0) | 6 (20.7) | 2 (15.4) | ||
| Flat | 7 (16.7) | 7 (18.9) | 0 (0) | 7 (24.1) | 0 (0) | ||
| Pitting | 27 (64.3) | 22 (59.5) | 5 (100.0) | 16 (55.2) | 11 (84.6) | ||
| Surgical method, n (%) | 0.322 | 0.152 | |||||
| Distal subtotal gastrectomy | 26 (61.9) | 21 (56.8) | 5 (100.0) | 15 (51.7) | 11 (84.6) | ||
| Proximal subtotal gastrectomy | 8 (19) | 8 (21.6) | 0 (0) | 6 (20.7) | 2 (15.4) | ||
| Total gastrectomy | 3 (7.2) | 3 (8.1) | 0 (0) | 3 (10.3) | 0 (0) | ||
| Celiac lymph node dissection | 5 (11.9) | 5 (13.5) | 0 (0) | 5 (17.3) | 0 (0) | ||
| Invasion depth, n (%) | 0.018 | 0.307 | |||||
| T1a | 19 (45.2) | 19 (51.4) | 0 (0) | 13 (44.8) | 6 (46.2) | ||
| T1b | 23 (54.8) | 18 (48.6) | 5 (100) | 16 (55.2) | 7 (53.8) | ||
| Histological type, n (%) | 0.028 | 0.654 | |||||
| Differentiated | 27 (64.3) | 26 (70.3) | 1 (20) | 18 (62.1) | 9 (69.2) | ||
| Undifferentiated | 15 (35.7) | 11 (29.7) | 4 (80) | 11 (37.9) | 4 (30.8) | ||
| Number of tumor lesions, n (%) | 0.710 | 0.498 | |||||
| Solitary | 41 (97.6) | 36 (97.3) | 5 (100.0) | 28 (96.6) | 13 (100.0) | ||
| Multiple | 1 (2.4) | 1 (2.7) | 0 (0) | 1 (3.4) | 0 (0) | ||
| Positive vascular invasion, n (%) | 5 (11.9) | 0 (0) | 5 (100.0) | < 0.001 | 0 (0) | 5 (38.5) | < 0.001 |
| Lauren classification, n (%) | 0.039 | 0.532 | |||||
| Intestinal type | 22 (52.4) | 21 (56.8) | 1 (20.0) | 15 (51.7) | 7 (53.8) | ||
| Diffuse | 13 (31.0) | 9 (24.3) | 4 (80.0) | 8 (27.6) | 5 (38.5) | ||
| Mixed | 7 (16.6) | 7 (18.9) | 0 (0) | 6 (20.7) | 1 (7.7) | ||
| Pattern of invasion, n (%) | < 0.001 | 0.001 | |||||
| IFN-A | 8 (19.0) | 8 (21.6) | 0 (0) | 6 (20.7) | 2 (15.4) | ||
| IFN-B | 26 (62.0) | 26 (70.3) | 0 (0) | 22 (75.9) | 4 (30.8) | ||
| IFN-C | 8 (19.0) | 3 (8.1) | 5 (100.0) | 1 (3.4) | 7 (53.8) | ||
| Positive horizontal resection margin, n (%) | 19 (45.2) | 18 (48.6) | 1 (20.0) | 0.227 | 10 (34.5) | 9 (69.2) | 0.036 |
| Positive vertical resection margin, n (%) | 21 (50.0) | 16 (43.2) | 5 (100.0) | 0.017 | 14 (48.3) | 7 (53.8) | 0.739 |
| Positive nerve invasion, n (%) | 4 (9.5) | 1 (2.7) | 3 (60.0) | < 0.001 | 0 (0) | 4 (30.8) | 0.002 |
| eCura score, n (%) | < 0.001 | 0.007 | |||||
| Low-risk group | 24 (57.1) | 24 (64.9) | 0 (0) | 18 (62.1) | 6 (46.2) | ||
| Moderate-risk group | 14 (33.3) | 13 (35.1) | 1 (20.0) | 11 (37.9) | 3 (23.1) | ||
| High-risk group | 4 (9.6) | 0 (0) | 4 (80.0) | 0 (0) | 4 (30.7) | ||
| Degree of radical endoscopic treatment (eCura), n (%) | 0.467 | 0.790 | |||||
| eCura-A | 1 (2.4) | 1 (2.7) | 0 (0) | 1 (3.5) | 0 (0) | ||
| eCura-B | 1 (2.4) | 1 (2.7) | 0 (0) | 1 (3.5) | 0 (0) | ||
| eCura-C1 | 11 (26.2) | 11 (29.7) | 0 (0) | 7 (24.1) | 4 (30.8) | ||
| eCura-C2 | 29 (69.0) | 24 (64.9) | 5 (100.0) | 20 (68.9) | 9 (69.2) | ||
| Ulcer, n (%) | 26 (61.9) | 22 (59.5) | 4 (80.0) | 0.375 | 16 (55.2) | 10 (76.9) | 0.180 |
| Range of lymph node dissection, n (%) | 0.409 | 0.101 | |||||
| D1 | 24 (57.1) | 22 (59.5) | 2 (40.0) | 19 (65.5) | 5 (38.5) | ||
| D2 | 18 (42.9) | 15 (40.5) | 3 (60.0) | 10 (34.5) | 8 (61.5) | ||
- Citation: Zheng Z, Bu FD, Chen H, Yin J, Xu R, Cai J, Zhang J, Yao HW, Zhang ZT. Factors associated with overall survival in early gastric cancer patients who underwent additional surgery after endoscopic submucosal dissection. World J Clin Cases 2021; 9(10): 2192-2204
- URL: https://www.wjgnet.com/2307-8960/full/v9/i10/2192.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i10.2192