Comparative profile for COVID-19 cases from China and North America: Clinical symptoms, comorbidities and disease biomarkers

Table 1 Characteristics of the study populations with coronavirus disease 2019 from China and North America

Characteristic	China		North America		P3 value
	Number of cases (n)1	Mean2 (95%CI)	Number of cases (n)1	Mean2 (95%CI)
Age	23088	50.6 (50.4-50.8)	37293	55.5 (55.4-55.6)	< 0.001
Male (%)	29755	52.6 (52.5-52.7)	36298	54.4 (54.2-54.5)	< 0.001
Severity (%)	26810	18.7 (12.8-24.6)	7824	25.1 (19.1-31.3)	< 0.001
Infection outcome (%)
ARDS	13524	14.5 (14.1-14.9)	1849	34.9 (33.9-36.1)	< 0.001
Heart failure	4847	10.6 (10.2-11.1)	2654	2.5 (2.4-2.6)	< 0.001
Septic shock	10886	4.0 (3.8-4.2)	2266	28.4 (27.3-29.5)	< 0.001
Acute kidney injury	12767	5.5 (5.4-5.7)	4761	26.7 (26.4-27.1)	< 0.001
Secondary infection	4617	15.3 (14.7-15.9)	807	5.3 (5.1-5.6)	< 0.001

¹n is the number of subjects assessed for each characteristic as per the source database[7].

²Weighted mean.

³Student’s t-test or Chi Square test. ARDS: Acute respiratory distress syndrome.