Liver cirrhosis in a child associated with Castleman's disease: A case report

Table 2 Patients with multicentric Castleman’s disease/TAFRO syndrome complicated by hepatobiliary diseases

Year	Age/sex	Diagnosis	Type	Pathological findings of the liver	Outcome	Ref.
1991	22/F	CD	Mixed	Liver cirrhosis associated with Budd-Chiari syndrome, an underlying disease	Liver transplantation waiting for Budd-Chiari syndrome	[14]
1995	50/M	CD	PC	Diffuse fibrosis	Death due to thrombocytopenia and massive gastrointestinal bleeding	[15]
	35/M	CD	PC	Cholestasis and peliosis hepatis	Unknown
2003	54/M	CD	Mixed	Nodular cirrhosis	Perform liver transplantation and maintain remission	[16]
2005	45/M	CD	PC	Nodular regenerative hyperplasia	PSL effective	[17]
2013	51/M	CD	-	Liver amyloidosis	Symptoms persist even after lymph node dissection	[18]
2016	56/M	TAFRO	Mixed	Expansion of portal area, interface hepatitis, pseudo biliary hyperplasia and cholangitis	Steroid pulse, PSL, tocilizumab, rituximab	[19]
2017	26/F	CD	PC	Fibrosis and plasma cell infiltration	PSL effective	[20]
This case	10/M	CD or TAFRO	Mixed	Portal vein area fibrosis, inflammatory cell infiltration, bile duct hyperplasia	PSL ineffective, tocilizumab improves inflammatory response

CD: Castleman's disease; PC: Plasma cell; PSL: Prednisolone.