Prognosis factors of advanced gastric cancer according to sex and age

Table 3 Multivariate analysis of factors influencing survival according to sex using a Cox proportional hazards model

Characteristic	Male			Female
	P value	HR	95%CI	P value	HR	95%CI
Age
≤ 60 yr		1.000			1.000
> 60 yr	0.001	1.882	1.601-2.213	0.136	1.204	0.943-1.536
Tumour size
≤ 5 cm		1.000			1.000
> 5 cm	0.001	1.443	1.212-1.718	0.001	1.610	1.239-2.090
Lymphovascular invasion
No		1.000			1.000
Yes	0.001	1.697	1.428-2.017	0.001	1.587	1.238-2.035
Lymph node metastasis
No		1.000			1.000
Yes	0.166	0.890	0.754-1.050	0.437	0.907	0.709-1.161
Depth of invasion
Muscularis propria	0.025	0.521	0.295-0.920	0.736	1.220	0.385-3.866
Sub-serosal	0.044	0.565	0.324-0.986	0.824	1.139	0.362-3.587
Serosal exposed	0.039	0.551	0.314-0.970	0.986	0.990	0.311-3.147
Serosal invasion	0.264	0.669	0.330-1.354	0.653	0.693	0.140-3.434
Histology
Tubular adenocarcinoma (well)		1.000			1.000
Tubular adenocarcinoma (moderate)	0.043	1.754	1.017-3.026	0.886	0.929	0.337-2.559
Tubular adenocarcinoma (poor)	0.010	2.029	1.181-3.486	0.739	0.844	0.312-2.282
Signet ring cell carcinoma	0.001	3.153	1.769-5.619	0.812	0.883	0.317-2.459
Mucinous adenocarcinoma	0.359	1.390	0.688-2.810	0.896	1.080	0.342-3.409

HR: Hazard ratio; CI: Confidence interval.