Prognosis factors of advanced gastric cancer according to sex and age

Table 2 Multivariate analysis of factors influencing survival using a Cox proportional hazards model

Characteristic	Overall survival			Recurrence-free survival
	P value	HR	95%CI	P value	HR	95%CI
Sex
Male		1.000			1.000
Female	0.434	0.943	0.813-1.093	0.292	0.925	0.801-1.069
Age
≤ 60 yr		1.000			1.000
> 60 yr	0.001	1.723	1.502-1.978	0.001	1.658	1.451-1.895
Tumour size
≤ 5 cm		1.000			1.000
> 5 cm	0.001	1.455	1.252-1.690	0.001	1.505	1.302-1.740
Lymphovascular invasion
No		1.000			1.000
Yes	0.001	1.678	1.450-1.943	0.001	1.676	1.455-1.931
Lymph node metastasis
No		1.000			1.000
Yes	0.047	0.866	0.752-0.998	0.111	0.894	0.780-1.026
Depth of invasion
Muscularis propria	0.102	0.654	0.394-1.088	0.160	0.696	0.419-1.155
Sub-serosal	0.125	0.676	0.410-1.115	0.200	0.721	0.437-1.189
Serosal exposed	0.080	0.636	0.383-1.055	0.142	0.685	0.413-1.135
Serosal invasion	0.287	0.705	0.370-1.342	0.272	0.697	0.366-1.189
Histology
Tubular adenocarcinoma (well)		1.000			1.000
Tubular adenocarcinoma (moderate)	0.036	1.783	1.038-3.061	0.069	1.562	0.967-2.523
Tubular adenocarcinoma (poorly)	0.008	2.070	1.211-3.538	0.026	1.716	1.067-2.759
Signet ring cell carcinoma	0.001	2.689	1.535-4.707	0.001	2.290	1.387-3.781
Mucinous adenocarcinoma	0.156	1.601	0.836-3.066	0.236	1.431	0.791-2.588

HR: Hazard ratio; CI: Confidence interval.