Retrospective Cohort Study
Copyright ©The Author(s) 2020.
World J Clin Cases. May 6, 2020; 8(9): 1600-1607
Published online May 6, 2020. doi: 10.12998/wjcc.v8.i9.1600
Table 1 Patient characteristics stratified by cardiorenal syndrome type 1 diagnosis
Patient charateristicsAll patients (n = 202)No-CRS-1 patients (n = 147) (72.8%)CRS-1 patients (n = 55) (27.2%)P value
Age (yr)67 (57-77)64 (65-72)77 (67-83)< 0.001
Gender: Male/female142/60106/4036/200.30
Creatinine admission (μmol/L)78.3 (66.9-97.7)72.2 (65.1-82.7)124.1 (102-174.2)< 0.001
Creatinine peak (μmol/L)87.1 (72.2-117)77.4 (70.4-89.8)142.6 (121.4-1.98)< 0.001
BUN at admission (μmol/L)13.2 (10.3-17.8)12.1 (10-14.2)21.4 (16-25.7)< 0.001
Urine output by 24 h (mL)1585 (900-2625)1700 (1100-2650)1200 (700-2300)0.0034
Furosemide use ≥ 120 mg/24 h79 (39.70)63 (43.45)16 (29.63)0.20
ΔNGAL (ng/dL)-8 [(-29)-17]-6 [(-24)-17]-13 [(-112)-20]0.14
NGAL peak (ng/dL)147 (81-245.5)153.5 (80-256)121 (86-188)0.31
NGAL cut-off (≥ 140 ng/mL)102 (50.50)79 (48.30)23 (41.82)0.20
Troponin I peak (μg/L)4.72 (0.36-34.51)2.21 (0.25-25.26)10.67 (1.52-47.76)0.02
NTproBNP peak (pg/mL)200 (93.60-559.0)203.5 (104.5-570.5)180.5 (89.0-475.0)0.68
K (mmol/L)3.9 (3.7-4.2)3.9 (3.7-4.1)4.2 (3.8-4.5)< 0.001
Hb (g/L)132 (121-143)134 (126-145)120 (105-133)< 0.001
Systolic arterial pressure (mmHg)135 (120-151)139 (120-151)135 (110-150)0.18
Dyastolic arterial pressure (mmHg)70 (60-80)70 (65-80)65 (55-75)0.01
Mean arterial pressure (mmHg)92 (82-107)94 (86-105)89 (75-100)0.04
EF ≤ 40%44 (32.35)34 (34.69)10 (26.32)0.35
Severe dilation left ventriculus1, n (%)22 (11.06)15 (10.34)7 (12.96)0.82
Catecolamine use, n (%)10 (4.95)7 (4.76)3 (5.45)0.8
IABP use, n (%)12 (5.94)6 (4.08)6 (12.76)0.07
CICU mortality, n (%)6 (3)3 (2)3 (5)0.3
1Dilation of the left ventriculus (see Ref. 15). CICU: Cardiac intensive care unit; EF: Ejection fraction; IABP: Intra-aortic balloon pump; CRS-1: Cardiorenal syndrome type 1; NGAL: Neutrophil gelatinase-associated lipocalin; BUN: Blood urea nitrogen.