Acute myeloid leukemia with t(11;19)(q23;p13.1) in a patient with a gastrointestinal stromal tumor undergoing imatinib therapy: A case report

Table 1 Summary of clinicopathologic data of the 11 patients with gastrointestinal stromal tumors who subsequently developed acute myeloid leukemia

No.	Age (yr)	Sex	Location of GIST	KIT expression/KIT mutation	AML type	Bone marrow cyto-genetics	Interval of GIST and leukemia	Administration of imatinib mesylate	Ref.
1	57	Male	Perirectal	+/ND	M4eo	46, XY, add(6) (p25), inv (16) (p13q22), trisomy 8	33	+	[12]
2	74	Male	ND	+/ND	NOS	ND	38	+	[12]
3	70	Female	Small bowel	+/ND	M2	46, XX, del(11)(9q21q23) 11q23 (MLLx2)	27	+	[12]
4	63	Female	Small bowel	+/ND	Preceded by MDS	ND	216	ND	[8]
5	84	Female	Small bowel	+/ND	NOS	ND	21	ND	[8]
6	40	Male	Small bowel	+/c.1689_1701 del	Promyelocytic leukemia	ND	30	ND	[8]
7	70	Female	Stomach	+/c.1689_1701 del	NOS	ND	153	ND	[8]
8	49	Male	Stomach	ND/ND	NOS	ND	252	ND	[8]
9	58	Female	Small bowel	+/ND	Acute myelomonocytic leukemia	ND	20	ND	[8]
10	63	Female	Stomach	+/ND		46, XX, t(11;19)(q23;p13.1)	96	+	The present case

GIST: Gastrointestinal stromal tumor; AML: Acute myeloid leukemia; ND: No data; NOS: Not otherwise specified; MDS: Myelodysplastic syndrome.