Depression and myocardial injury in ST-segment elevation myocardial infarction: A cardiac magnetic resonance imaging study

Table 1 Baseline characteristics of the patients by Patient Health Questionnaire-9 score

Variables	Overall (n = 107)	PHQ-9 score < 10 (n = 88)	PHQ-9 score ≥ 10 (n = 19)	P value
Demographics
Age, yr	56.5 ± 10.5	56.2 ± 10.7	58.1 ± 9.8	0.469
Male	86 (80.4)	71 (80.7)	15 (78.9)	0.863
Medical history
History of diabetes mellitus	29 (27.1)	23 (26.1)	6 (31.6)	0.628
History of hypertension	44 (41.1)	34 (38.6)	10 (52.6)	0.261
History of cerebrovascular disease	12 (11.2)	11 (12.5)	1 (5.3)	0.365
Prior PCI	3 (2.8)	2 (2.3)	1 (5.3)	0.474
Current smoking	74 (69.2)	61 (69.3)	13 (68.4)	0.939
Clinical presentation
PHQ-9 score	4.9 ± 5.1	2.9 ± 2.6	14.3 ± 2.8	≤ 0.001
SBP on admission, mmHg	125.9 ± 23.8	125.7 ± 22.4	127.0 ± 30.1	0.823
Heart rate on admission, bpm	78.9 ± 17.2	77.3 ± 17.1	86.4 ± 16.0	0.037
Laboratory results on admission
Troponin-I, ng/mL	27.0 (8.6, 58.5)	24.7 (9.0, 56.6)	32.8 (3.5, 80.0)	0.504
Creatinine, µmol/l	70.2 ± 16.3	67.9 ± 14.8	80.8 ± 18.9	0.002
Albumin, g/L	40.5 ± 3.3	40.4 ± 3.2	40.7 ± 4.2	0.789
Hemoglobin, g/L	139.9 ± 22.5	139.6 ± 22.8	141.6 ± 21.5	0.723
Fasting glucose, mmol/L	7.38 ± 2.92	7.37 ± 2.96	7.43 ± 2.83	0.936
BNP, ng/L	111 (58, 239)	107 (58, 232)	180 (53, 473)	0.293
Total cholesterol, mmol/L	4.83 ± 1.13	4.73 ± 1.14	5.31 ± 0.99	0.041
Low-density lipoprotein, mmol/L	3.07 ± 1.00	2.99 ± 1.00	3.43 ± 0.93	0.08
High-density lipoprotein, mmol/L	0.99 ± 0.26	0.97 ± 0.26	1.07 ± 0.27	0.137
Triglycerides, mmol/L	1.46 (0.99, 2.26)	1.46 (0.99, 2.21)	1.47 (0.60, 3.29)	0.929
Percutaneous coronary intervention details
Door-to-balloon time, min	80.0 (50.0, 120.0)	81.5 (49.9, 127.8)	67.3 (50.0, 103.0)	0.52
Culprit vessels				0.294
Right coronary artery	52 (48.6)	45 (51.1)	7 (36.8)
Left anterior descending artery	45 (42.1)	34 (38.6)	11 (57.9)
Left circumflex artery	10 (9.3)	9 (10.2)	1 (5.3)
Use of intra-aortic balloon pump	3 (2.8)	1 (1.1)	2 (10.5)	0.025
Killip class I on admission	95 (88.8)	80 (90.9)	15 (78.9)	0.134
TIMI flow grade 3 post-PCI	105 (98.1)	86 (97.7)	19 (100)	0.507

Data are presented as median (IQR), n (%), or mean ± SD.PHQ-9: Patient Health Questionnaire-9; PCI: Percutaneous coronary intervention; SBP: Systolic blood pressure; bpm: Beats per minute; BNP: Brain natriuretic peptide.