Clinical significance and prognostic value of tumor necrosis factor-α and dickkopf related protein-1 in ankylosing spondylitis

doi:10.12998/wjcc.v8.i7.1213

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Apr 6, 2020; 8(7): 1213-1222
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1213

Table 2 Diagnostic value of dickkopf-related protein-1 and tumor necrosis factor-α in ankylosing spondylitis by receiver operating characteristic curve

	DKK-1	TNF-α	Combination
AUC	0.752	0.904	0.934
95%CI	0.684-0.820	0.859-0.950	0.900-0.967
Cutoff value	87.02 pg/mL	18.79 ng/L
Sensitivity	78.76%	79.65%	82.30%
Specificity	66.00%	95.00%	97.00%

TNF-α: Tumor necrosis factor-α; DKK: Dickkopf-related protein-1; AUC: Area under the curve.

Citation: Xiong JH, Liu J, Chen J. Clinical significance and prognostic value of tumor necrosis factor-α and dickkopf related protein-1 in ankylosing spondylitis. World J Clin Cases 2020; 8(7): 1213-1222
URL: https://www.wjgnet.com/2307-8960/full/v8/i7/1213.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i7.1213