Efficacy of totally laparoscopic compared with laparoscopic-assisted total gastrectomy for gastric cancer: A meta-analysis

Table 2 Intraoperative and postoperative information in all included studies

Outcomes	Number of studies	Sample size		Heterogeneity(P, I2)	Effectmodel	Overall effect size	95%CI of overall effect	P value
		TLTG	LATG
Operation time (min)	7	448	748	0.29, 18%	R	WMD = -4.84	-11.62-1.95	0.16
Anastomotic time (min)	2	135	174	0.009, 85%	R	WMD = 9.36	-1.32-20.04	0.09
Tumor size (cm)	7	752	968	0.009, 65%	R	WMD = -0.43	-0.89-0.04	0.07
Proximal margin (cm)	5	611	489	< 0.001, 87%	R	WMD = -0.56	-1.39-0.27	0.18
Intraoperative blood loss (mL)	6	358	725	< 0.001, 76%	R	WMD = -35.37	-61.69--9.06	0.008
Number of lymph nodes removed	6	727	943	0.06, 52%	R	WMD = 3.11	0.63-5.60	0.01
Postoperative VAS pain scores
Peak pain score	2	511	289	0.09, 66%	R	WMD = 0.17	-0.71-1.05	0.70
POD #1 (8 am)	3	541	313	0.73, 0%	R	WMD = -0.01	-0.22-0.19	0.89
POD #3 (8 am)	3	541	313	0.02, 73%	R	WMD = -0.17	-0.61-0.27	0.45
POD #5 (8 am)	2	451	290	0.40, 0%	R	WMD = -0.19	-0.39-0.01	0.07
Time to first flatus (d)	5	301	678	0.41, 0%	R	WMD = 0.07	-0.09-0.22	0.40
Time to first oral intake (d)	6	331	702	0.16, 37%	R	WMD = -0.31	-0.67-0.06	0.10
Postoperative hospital stay (d)	6	331	702	0.18, 34%	R	WMD = -0.78	-1.74-0.19	0.11
Anastomosis-related complications	8	869	1014	0.29, 18%	R	OR = 0.73	0.38-1.40	0.34
Overall postoperative complications	6	701	512	0.57, 0%	R	OR = 1.00	0.75-1.32	0.97

TLTG: Totally laparoscopic total gastrectomy; LATG: Laparoscopic-assisted total gastrectomy; F: Fixed; R: Random; WMD: Weighted mean difference; OR: Odds ratio; CI: Confidence interval; VAS: Visual analog scale; POD: Postoperative day.