Identification of key genes and pathways in gastric signet ring cell carcinoma based on transcriptome analysis

Figure 4 Expression of MAGEA2/3/6, MAGEA4, and REG1B in gastric signet ring cell carcinoma. Data were collected from TCGA and GTEx data using GEPIA (http://gepia.cancer-pku.cn/index.html). A: FPKM of genes in transcriptome sequencing data in 408 gastric carcinoma tissues (T) and 211 normal tissues (N); B: Survival rate calculated by the Kaplan-Meier method in patients separated according to the median expression level of each gene (95%CI); C: Quantitative real-time PCR was used to measure the relative expression levels of the indicate genes in 27 gastric signet ring cell carcinoma samples and 29 non-gastric signet ring cell carcinoma samples. The results were normalized to the endogenous GAPDH RNA control. GSRCC: Gastric signet ring cell carcinoma.