Complete response to trastuzumab and chemotherapy in recurrent urothelial bladder carcinoma with HER2 gene amplification: A case report

doi:10.12998/wjcc.v8.i3.594

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Feb 6, 2020 (publication date) through Oct 5, 2024

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Feb 6, 2020; 8(3): 594-599
Published online Feb 6, 2020. doi: 10.12998/wjcc.v8.i3.594

Table 3 Selected trials of anti-HER2 agents in advanced bladder cancer

Regimen	Phase	No of patients	Prior chemotherapy	Target enrichment	OR (%)	mOS (mo)
Carboplatin/ paclitaxel/ gemcitabine/trastuzmab	I/II	57	No	Yes	70	14.1
Lapatinib	II	59	Yes	No	1.7	4.5
Lapatinib maintenance after first-line chemotherapy	II/III	116	No	Yes	14	12.6

OR: Overall response; mOS: Median overall survival.

Citation: Jiang Q, Xie MX, Zhang XC. Complete response to trastuzumab and chemotherapy in recurrent urothelial bladder carcinoma with HER2 gene amplification: A case report. World J Clin Cases 2020; 8(3): 594-599
URL: https://www.wjgnet.com/2307-8960/full/v8/i3/594.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i3.594