Virus load and virus shedding of SARS-CoV-2 and their impact on patient outcomes

Table 2 Univariate and multivariate regression analyses of the risk factors for viral shedding

Variables	Univariate		Multivariate
	HR (95%CI)	P value	HR (95%CI)	P value
Sex, male	1.1 (0.7, 1.6)	0.757	0.8 (0.5, 1.3)	0.422
Age (yr)
< 60	Reference
≥ 60	0.5 (0.4, 0.8)	0.002	0.6 (0.4, 1.0)	0.030
Diabetes	0.9 (0.5, 1.8)	0.870	1.4 (0.7, 2.7)	0.370
IVIG	0.5 (0.3, 0.7)	< 0.001	0.6 (0.3, 1.2)	0.182
Antibiotics	0.5 (0.4, 0.8)	0.002	0.7 (0.4, 1.3)	0.273
Steroids	0.5 (0.3, 0.7)	<0.001	0.8 (0.4, 1.7)	0.588
PAO2/FIO2
< 300	Reference
≥ 300	1.3 (0.8, 2.2)	0.247	1.0 (0.5, 1.7)	0.898
Chloroquine	26.8 (3.0, 239.3)	0.003	19.0 (1.9, 186.2)	0.012
NLR	1.0 (0.9, 1.0)	0.386	1.0 (1.0, 1.1)	0.632

IVIG: Intravenous immunoglobulin; NLR: Neutrophil-lymphocyte ratio.