Case Report
Copyright ©The Author(s) 2020.
World J Clin Cases. Dec 6, 2020; 8(23): 6197-6205
Published online Dec 6, 2020. doi: 10.12998/wjcc.v8.i23.6197
Table 2 Cases diagnosed as polyostotic fibrous dysplasia
Ref.
Year
Sex
Age
Location
Appendix
Treatment
Outcome
Sagmeister et al[12]2016F27Throughout the skeleton. Transverse fracture of the distal right femurContinuous lesions, extensive bone expansion, cyst formation, cortical lossSkin traction for 8 wk. Intensive physiotherapy for the fractureRecovered well, returning to baseline 3 mo later
Wu et al[2]2014F38Sternum, thoracic spine, ribs, right femur, and tibiaMultiple lytic, expansile lesions, continuous pathologic fractures in the thoracic spineSurgical therapy. Diphosphate therapy with Vit D and calciumCompletely recovered. Able to participate in daily life and work 2 yr later
Kodama et al[10]2012F8Right pelvis, bilateral femurs, and fibulaDiscontinuous lesionsThigh coxa valga osteotomy and plate fixation. Diphosphate therapyNo complaints of severe pain in lower extremity. Low bone turn-over rate
Aras et al[9]2012M48Cranium, left hemithorax, bilateral upper, lower extremities, and pelvic bonesContinuous lesions, bladder cancerNo treatment reportedNo outcome reported
Boston et al[8]1994M3.3Proximal left femur and proximal left humerusAlbright-McCune syndrome, no café-au-lait pigmentation, Cushing syndromeBilateral adrenalectomy at 7-yr-old with steroid replacementCushing syndrome removed. Still with prepubertal and elevated liver enzyme
Lourenço et al[11]2015F17 d Multiple lesions with fracture in left ulnaMultiple organs involved, Café-au-lait pigmentation, mosaic GNAS gene mutationMetyrapone therapy for Cushing syndromeCushing syndrome recovered. Death due to respiratory infection
The current caseF27Left ischium, left distal fibula, calcaneus, and talusDiscontinuous lesions, intractable bone pain, Cushing syndromeDiphosphate therapyStill severe pain. Difficulty participating in daily life and job