Overexpression of CD155 is associated with PD-1 and PD-L1 expression on immune cells, rather than tumor cells in the breast cancer microenvironment

Table 3 Association between CD155 expression and cell counts of tumor infiltrating lymphocytes phenotypes¹

TILs phenotypes	CD155 expression		P value
	Negative (n = 78)	Positive (n = 48)
CD4+ TILs, mean ± SD	54 ± 46	87 ± 93	0.041
CD4+/PD-1+ TILs, mean ± SD	20 ± 24	47 ± 57	0.002
CD4+/PD-1- TILs, mean ± SD	34 ± 30	41 ± 45	0.658
CD8+ TILs, mean ± SD	21 ± 20	37 ± 44	0.040
CD8+/PD-1+ TILs, mean ± SD	4 ± 5	7 ± 13	0.069
CD8+/PD-1- TILs, mean ± SD	17 ± 17	30 ± 35	0.040

¹Wilcoxon rank sum test. TILs: Tumor infiltrating lymphocytes.