Overexpression of CD155 is associated with PD-1 and PD-L1 expression on immune cells, rather than tumor cells in the breast cancer microenvironment

Table 2 Association between CD155 expression and percentage of tumor infiltrating lymphocytes phenotypes¹

	CD155 expression		P value
TILs phenotypes	Negative (n = 78)	Positive (n = 48)
CD4+ TILs, mean ± SD	60% ± 22%	61% ± 22%	0.788
CD4+/PD-1+ TILs, mean ± SD	21% ± 20%	30% ± 19%	0.004
CD4+/PD-1- TILs, mean ± SD	39% ± 20%	31% ± 19%	0.032
CD8+ TILs, mean ± SD	23% ± 13%	24% ± 11%	0.342
CD8+/PD-1+ TILs, mean ± SD	4% ± 5%	5% ± 5%	0.280
CD8+/PD-1- TILs, mean ± SD	19% ± 10%	20% ± 9%	0.437

¹Wilcoxon rank sum test. TILs: Tumor infiltrating lymphocytes.