Oral granuloma in a pediatric patient with chronic graft-versus-host disease: A case report

Table 1 Cases of transplant-related calcineurin inhibitor-induced oral inflammatory nodules with chronic and oral graft-versus-host disease

Year	Ref.	Age at transplant	Sex	Primary disease	ChronicGVHD	Oral GVHD	Calcineurininhibitor	Location	Treatment	Malignancy	CMV
1994	Lee et al[3]	19	M	AML	O	O	CsA	Buccal mucosa	Excision	No	Negative
1994	Lee et al[3]	45	M	CLL	O	O	CsA	Buccal mucosa	Excision	No	Negative
1994	Woo et al[2]	36	F	AML	O	O	CsA	Buccal mucosa, lower lip	Excision	No	Negative
1996	Woo et al[2]	27	F	CML	O	O	CsA	Buccal mucosa	Excision	No	Not stated
1996	Woo et al[2]	31	M	AML	O	O	CsA	Tongue	Excision	No	Not stated
1996	Woo et al[2]	50	F	Myelodysplasia	O	O	CsA	Buccal mucosa	Excision	No	Not stated
1996	Woo et al[2]	29	F	AML	O	O	CsA	Buccal mucosa	Excision	No	Not stated
1996	Woo et al[2]	33	F	CML	O	O	CsA	Tongue	Excision	No	Not stated
1996	Woo et al[2]	34	M	AML	O	O	CsA	Tongue	Excision	No	Not stated
2007	Al-Mohaya et al[5]	8	M	ALL	O	O	CsA	Tongue	Excision	No	Not stated
2007	Al-Mohaya et al[5]	3	M	PNP deficiency	O	O	FK506	Tongue	Excision	No	Not stated
2009	Suh et al[6]	46	M	Multiple myeloma	O	O	CsA	Tongue	Excision	No	Not stated
2016	Cheney-Peters et al[7]	9 and 11	M	Fanconi animia	O	O	FK506	Tongue	Excision	No	Not stated
2016	Cheney-Peters et al[7]	19	M	Hodgkin's disease	O	O	CsA	Buccal mucosa	Excision	No	Not stated
2020	Present case	11 mo and 1	F	PID	O	O	FK506	Buccal mucosa, lower lip, tongue	Natural disappearance or excision	No	Negative

GVHD: Graft-versus-host disease; CMV: Cytomegalovirus; AML: Acute myelocytic leukemia; CLL: Chronic lymphocytic leukemia; CML: Chronic myelogenous leukemia; ALL: Acute lymphocytic leukemia; PNP: Purine nucleoside phosphorylase; PID: Primary immunodeficiency disease; CsA: Cyclosporine A; FK506: Tacrolimus.