Anterior bone loss after cervical disc replacement: A systematic review

Table 1 Studies included in the systematic review

Ref.	Yr	Study type	Level of evidence	Number and type of artificial disc	Sex	Age (yr)	Follow-up
Ren et al[22]	2011	Prospective and nonrandomized study	3	Total (Bryan): 45 patients and 51 implants	19 Female; 26 Male	46 (31-50)	Mean 35 (24-70) mo
Hacker et al[23]	2013	Randomized controlled study	2	Total 51 patientsBryan: 32 patientsPrestige-LP: 19 patients	27 Female; 24 Male	-	1, 6, 12, 24 wk and 12, 24, 48, 60 mo
Kim et al[24]	2015	Prospective registry with retrospective analysis	3	Total (Bryan): 37 patients	13 Female; 24 Male	45.4 (27-55)	1, 3, 6, 12, 24, 36 mo, mean 60.1 (42-113) mo
Heo et al[25]	2017	Retrospective observational study	3	Total (Baguera-C): 48 patients	30 Female; 18 Male	50.1 ± 7.4	1, 6, 12, 24 mo, mean 32.3 ± 3.3 mo
Kieser et al[26]	2018	Retrospective observational study	3	Total 145 patients and 193 implants Bryan: 32 patients, 56 implants, Discocerv: 38 patients, 44 implants; Baguera-C: 44 patients, 56 caudal implants; Mobi-C: 31 patients, 37 implants	78 Female; 67 Male	45 (25-65)	3, 6, 12, 24, 36, 48, 60 mo, mean 6.2 (5-10) yr
Kieser et al[27]	2019	Retrospective observational study	3	Total 114 patients and 156 implants; Bryan: 32 patients, 56 implants; Discocerv: 38 patients, 44 implants; Baguera-C: 44 patients, 56 caudal implants	65 Female; 49 Male	45.3 (28-65)	6 wk, 3, 6, 9, 12, 24 mo, 5 yr, maximum 8 yr