Copyright
©The Author(s) 2020.
World J Clin Cases. Nov 6, 2020; 8(21): 5235-5249
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5235
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5235
Table 1 Features of the studies included in this analysis
Ref. | Design | Patient type | Treatments | N | M/F | Age, yr, range (mean) | BMI, kg/m2 | Duration |
Yin et al[23], 2000 | Randomized, OL | NAFLD + diabetes | PPC + ADs vs ADs | 125 | 73/52 | 42–78 (59) | N/A | 84 d |
Poongothai et al[25], 2005 | Prospective, OL | NAFLD + type 2 diabetes | PPC + ADs | 22 | 11/11 | (41) | 28.2 | 6 mo |
Arvind et al[26], 2006 | Prospective, non-randomized, DB | NAFLD + diabetes or obesity | PPC vs ursodeoxycholic acid | 40 | NA | NA | NA | 3 mo |
Sun et al[21], 2008 | Prospective, randomized, OL | NAFLD + type 2 diabetes | PPC + metformin vs metformin | 74 | 40/34 | 28–60 (42) | NA | 12 wk |
Wu et al[22], 2009 | Prospective, randomized, OL | NAFLD + type 2 diabetes | PPC + usual care vs usual care | 100 | 64/36 | (55) | NA | 1 mo |
Li et al[18], 2013 | Prospective, randomized, OL | NAFLD + diabetes | PPC + metformin vs metformin | 86 | 57/29 | (51) | NA | 6 wk |
Sas et al[19], 2013 | Prospective, randomized, OL | NASH + type 2 diabetes | PPC + metformin vs metformin | 189 | NA | NA | NA | 6 mo |
Dajani et al[24], 2015 | Prospective, OL | NAFLD ± type 2 diabetes or hyperlipidemia | Essential phospholipid | 324 | 176/148 | 21–69 (43.5) | 29.3 | 72 wk |
Shan et al[20], 2015 | Prospective, randomized, OL | NASH + obesity | PPC vs Chinese medicine (Quzhi hepatoprotection recipe) | 60 | 38/22 | 18-55 (41.3) | NA | 8 wk |
Li et al[17], 2017 | Prospective, randomized, OL | NAFLD + diabetes | PPC + Chinese medicine (Shugan Huazhuo recipe) vs PPC | 80 | 44/36 | 29-63 (48) | NA | 3 mo |
- Citation: Dajani AI, Popovic B. Essential phospholipids for nonalcoholic fatty liver disease associated with metabolic syndrome: A systematic review and network meta-analysis. World J Clin Cases 2020; 8(21): 5235-5249
- URL: https://www.wjgnet.com/2307-8960/full/v8/i21/5235.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v8.i21.5235