Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma

doi:10.12998/wjcc.v8.i21.5139

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Nov 6, 2020; 8(21): 5139-5148
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5139

Table 4 Molecular analysis of all patients

	Adenocarcinoma, n = 62	Squamous cell carcinoma, n = 11	Adenosquamous carcinoma, n = 3	NSCLC-NOS, n = 5
*EGFR* mutation
Exon 19
E746-A750del (1)	2	0	0	0
E746-A750del (2)	4	0	0	0
L747-T751del	2	0	0	0
L747-S752del	1	0	0	0
L747-A750del	1	0	0	0
Exon 21			0
L858R	8	0	1	0
L861Q	2	0	0	0
*KRAS* mutation
Exon 2
G12C	3	1	0	0
G12D	2	0	0	0
G12V	2	0	0	0
G12L	1	0	0	0
*ROS-1* (FISH) positive	1	0	0	0
ALK (Ventana IHC) positive	5	0	0	0

NSCLC-NOS: Non-small cell lung carcinoma-not otherwise specified; ALK: Anaplastic lymphoma kinase; FISH: Fluorescence in situ hybridization; IHC: Immunohistochemistry.

Citation: Su W, Tian XD, Liu P, Zhou DJ, Cao FL. Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma. World J Clin Cases 2020; 8(21): 5139-5148
URL: https://www.wjgnet.com/2307-8960/full/v8/i21/5139.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i21.5139